Nanoparticles are so small in size that they can enter cells and organelles to interact with DNA, proteins, and enzymes as they circulate throughout the body. Therefore, nanotechnology is used to detect disease in a very small volume of cells or tissues [1]. As mentioned above; commonly used nanoparticles are such as gold nanoparticles, silver nanoparticles, quantum dots and magnetic nanoparticles. Gold nanoparticles have a unique stability against oxidation which makes them useful in diagnostics. Its advantages, such as very little or no toxicity, much better contrast agents for imaging, and improved surface- and distance- and refractive index-dependent spectroscopic properties compared to other nanoparticles, make it the best choice to enable the early disease detection [2, 3]. The use of nanoparticles for expert detection is a topic of interest that is being discovered passively for many applications [4]. First, the ability of a nanoparticle to identify a tissue of interest is perhaps the most potential capability in nanotechnology. Nanoparticles are used selectively...
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