Today, supply chains play an important role in determining the position of companies in their competitive environment. In this research, a three-tier multi-product supply chain was modeled to minimize the total cost. Then, the mathematical model analyzed considering disruptions based on three deferred sales policies: backorders, lost sales and outsourcing. Model solved efficiently by MATLAB software. The results show that the algorithm proposed by this research can neutralize the effect of outages and cause a significant reduction in the total system cost. The model is useful in helping decision makers take an active approach to maintaining business benefits when supply chain disruptions occur. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get Original Essay The survival of organizations is due to their ability to offer better outlets over a wider range, lower costs than competitors, faster performance and deliver the desired results (from a variety of aspects, such as quality, performance, costs , innovation and delivery). The delivery of such outcomes depends on the organization's ability to manage the flow of materials, information and money into and out of the organization. This flow is known as the supply chain. In today's competitive market, supply chain coordination (SCC) is of great importance. In the absence of coordination, the members of the scientific committee optimize their decisions independently. Supply chains can be complex and long and involve a large number of different trading partners, and their problems and issues are inevitable. Failure to resolve these issues will result in customer dissatisfaction and lost sales and impose many costs on organizations. World-class companies owe many of their successes to supply chain management, which is why supply chain has become a popular management discourse in recent decades. Since supply chain circuits are independent economic entities, creating a mechanism that can coordinate the activities and objectives of these entities in order to optimize the overall performance of the system is a key issue in supply chain management. In general, traditional supply chain research focused on making decisions under ideal conditions, where demand was defined and the manufacturer had complete market information; but in the real world, complete market information is rarely available, and obtaining demand distribution can be difficult and even impossible. In a dynamic and complex supply chain environment, uncertainty is considered a major concern. Demand uncertainty is also an important issue in the world of science and industry. These demand uncertainties have posed major challenges to supply chain management, leading to a reduction in real income. To account for uncertainty and its effects, you need to pay attention to sources of uncertainty, which are disruptions or interruptions in all parts of the supply chain. Many studies have been conducted on the main field of this research, the supply chain; many of the existing studies conducted in this field are qualitative articles and there are no quantitative modeling issues. While such studies play an important role in explaining new topics or learning key concepts, their application is.