IntroductionParsley, Petroselinum Crispum is an herb used for a large myriad of medical conditions such as urinary tract infections, kidney stones, gastrointestinal disorders, constipation, jaundice, flatulence, indigestion, colic, diabetes, bronchitic cough, asthma, edema, osteoarthritis, anemia, hypertension, prostate and spleen disorders (1, 2). Parsley contains volatile oils, carotenoids, vitamins B1, B2, C and K (1, 2). The volatile component of the oil could be further broken down into apiole, myristicin, furanocaumarins, phenyl propanoids, phanthalides, tocopherol, ascorbic acid, and various terpenoic compounds (1, 3-5). The volatile compounds in the oil allow parsley to induce a number of medical effects such as antimicrobial, antirheumatic, appetite stimulant, antispasmodic, digestive, laxative, antihypertensive, diuretic, hypouricemic, antioxidant, and estrogenic (1-3, 5, 6) Parsley has traditionally been used as a diuretic in folk medicine (1, 7). Despite its use and widespread reputation as a diuretic agent, scientific evidence of its function was not available until it was demonstrated in the works of Kreydiyyeh et al. in 2002 (7). The demonstration involved rat models that were offered an aqueous extract of parsley seeds and drinking water. Concluding with the results of a significant increase in urine flow in rats that had parsley seed extract in their drinking water over a 24-hour period, parsley as a diuretic agent has been scientifically recognized (7). Parsley used as a diuretic is best described by its aquaretic effect in which urine volume increases but sodium excretion remains unchanged (1, 2). Apiole and myristicin are the two main components responsible for the intake of aquarium...... middle of paper ......rsley (Petroselinum Crispum) on the urinary excretion of apigenin, blood antioxidant enzymes and blood biomarkers Oxidative stress in human subjects. The British Journal of Nutrition. 1999 June;81(6):447-55. PubMed PMID: 10615220. Epub 2000/01/01. ing.5. Thieves J, Tyler VE. Tyler's Favorite Herbs: The Therapeutic Use of Phytomedicines: Taylor & Francis; 1999.6. Kreydiyyeh SI, Usta J, Kaouk I, Al-Sadi R. The mechanism underlying the laxative properties of parsley extract. Phytomedicine: international journal of phytotherapy and phytopharmacology. September 2001;8(5):382-8. PubMed PMID: 11695882. Epub 2001/11/07. ENG.7. Kreydiyyeh SI, Usta J. Diuretic effect and mechanism of action of parsley. Journal of Ethnopharmacology. 20023//;79(3):353-7.8. Khan IA, Abourashed EA. Leung's Encyclopedia of Common Natural Ingredients: Used in Foods, Drugs, and Cosmetics: Wiley; 2011.