The cell is the smallest structural and functional unit of an organism. A cell is typically microscopic and consists of cytoplasm, a nucleus and is enclosed in a membrane. For information, a cell also has the same reproduction as human, animal and plant. Because of Rudolf Virchow (1855), a German physician said that “Where a cell exists, there must have been a pre-existing cell, just as the animal arises only from an animal and the plant only from a plant.” This concept can be concluded with the Latin axiom “Omniscellularecellula”, which means “Every cell from a cell”. It demonstrates that the continued life of the cell by carrying out cellular reproduction. In order for the cell to perform reproduction, the cell must perform division. For division to occur, a certain process or sequence that we call the cell cycle must occur. Based on Ching et al. (2011) the cell cycle is the sequence of phases that the cell goes through between one cell division and the next. According to Reece, Urry, Cain, Wasserman, Minorsky and Jackson (2011) the cell cycle is divided into three phases: the G1 phase (“first gap”), the S phase (“synthesis”) and the G2 phase (“second gap”). ”). The period between the mitotic divisions, which are G1, S, and G2, is called interphase. After three phases, the process will occur through mitosis and cytokinesis. It was included in the mitotic phase (M phase) which represents the shortest part of the cell cycle. Mitosis is the process by which a cell will divide by replication and divide the original chromosomes to obtain two new cells. These two cells will be identical to the original one. According to Karp (1999), mitosis is most of the metabolic activities of the cell, including transcription and translation, are reduced and the cell becomes...... middle of paper....... (2000 ). The cell a molecular approach (2nd ed.). Washington, DC: ASM Press.Escobedo,Y. (2005). Mitosis and meiosis. Retrieved from http://biology.unm.edu/ccouncil/Biology_201/Homework/Review%20Tools/Mitosis%20and%20Meiosis.pdf Ishiguro, K., & Watanabe, Y. (2007). Chromosome cohesion in mitosis and meiosis.Journal of Cell Science,120, 367-369.Karp, G. (1999). Concepts and experiments in cellular and molecular biology (2nd ed.). America, A: John Wiley & Sons, Inc. McIntosh, J. R., & McDonald, K. L. (1989). The mitotic spindle. Sci. Am,261, 48–56.Reece, J.B., Urry, L.A., Cain, M.L., Wasserman, S.A., Minorsky, P.V., & Jackson, R.B. (2011). Campbell Biology (9th ed.). San Francisco, CA:Pearson Education, Inc. Sharp, D. J., Rogers, G. C., & Scholey, J. M. (2000). Microtubule motors in mitosis. Nature, 407, 41-47. Appendix 1 Figure 1. Mitosis